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Abstract #1362

Neural mechanism on hypofunction of working memory maintenance with anxiety-provoking distracter in patients with obsessive compulsive disorder and generalized anxiety disorder

Gwang-Won Kim 1 , Jong-Chul Yang 2 , and Gwang-Woo Jeong 1,3

1 Research Institute of Medical Imaging, Chonnam National University Medical School, Gwang-ju, Korea, 2 Psychiatry, Chonbuk National University Hospital, Jeong-ju, Korea, 3 Department of Radiology, Chonnam National University Medical School, Gwang-ju, Korea

Patients with obsessive compulsive disorder (OCD) and generalized anxiety disorder (GAD) are associated with abnormalities in the processing and regulation of anxiety as well as cognitive deficits. The purpose of this study was to discriminate the brain activation patterns associated with the anxiety-provoking distracter during the working memory (WM) maintenance for the human faces between patients with OCD and GAD, and healthy controls by using a function magnetic resonance imaging (fMRI).

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