Abstract #1407
An 8 month longitudinal study of T1 measures in MS patients using 3D MPnRAGE
Steven R Kecskemeti 1 , Andrew L Alexander 1,2 , and Aaron S Field 3
1
Waisman Center, University of Wisconsin,
Madison, Wisconsin, United States,
2
Medical
Physics, University of Wisconsin, Madison, Wisconsin,
United States,
3
Radioilogy,
University of Wisconsin, Madison, Wisconsin, United
States
This study presents a longitudinal study of 8 monthly
scans using 3D MPnRAGE of two volunteers with multiple
sclerosis. T1 maps of normal appearing white matter and
gray matter are highly reproducible as determined by the
temporal coefficient of variation. Coefficient of
variation for a WM lesion that appeared during the study
was approximately 8x larger than normal appearing WM,
suggesting coefficient of variation of T1 across time
may be a useful biomarker to describe progression or
treatment of MS.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
