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Abstract #1475

Multi-stage three-dimensional UTE lung imaging by image-based self-gating

Marta Tibiletti 1 , Jan Paul 2 , Andrea Bianchi 3 , Stefan Wundrak 2 , Wolfgang Rottbauer 2 , Detlef Stiller 3 , and Volker Rasche 1,2

1 Core Facility Small Animal MRI, Ulm University, Ulm, Baden-Wrttemberg, Germany, 2 Internal Medicine II, University Hospital Ulm, Ulm, Baden-Wrttemberg, Germany, 3 Target Discovery Research, In-vivo imaging laboratory, Boehringer Ingelheim Pharma GmbH & Co. KG, Baden-Wrttemberg, Germany

In this work we combine image-based self-gating (img-SG) with ultra-short TE (UTE) 3D acquisition for lung imaging to allow effective respiratory gating during free breathing. The proposed method is also compared with k-space center self-gating (DC-SG). Successful retrospective extraction of respiratory signal from low definition, high temporal resolution images was obtained. While DC-SG signals requires to be strongly band-pass filtered which results in a sinusoidal shaped signal, img-SG permits direct visualization of the respiratory movement and therefore provides better outcome.

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