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Abstract #1482

First clinical lung MRI using an Active Breathing Coordinator

Evangelia Kaza 1 , David J Collins 1 , Richard Symonds-Tayler 1 , Fiona McDonald 2 , Helen A McNair 3 , Erica Scurr 2 , Dow-Mu Koh 2 , and Martin O Leach 1

1 CR-UK Cancer Imaging Centre, Institute of Cancer Research London and Royal Marsden Hospital, London, United Kingdom, 2 The Royal Marsden NHS Foundation Trust, London, United Kingdom, 3 Department of Radiotherapy, Royal Marsden NHS Foundation Trust and Institute of Cancer Research, Sutton, United Kingdom

An MR compatible Active Breathing Coordinator (ABC) system was applied for the first time for MRI of lung cancer patients using the same lung volumes and positioning as for radiotherapy planning. The morphological and functional MR images acquired under ABC control were compared with analogous CT images using radiotherapy treatment planning software. There was very good MR-CT intermodality tumour and organ position reproducibility, thus demonstrating the clinical potential of MR-ABC. Continuous MRI with simultaneous acquisition of ABC respiratory volume curves can additionally inform tumour motion tracking and Fourier Decomposition Analysis (FDA).

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