Abstract #1552
Importance of Intravenous Contrast Administration to Improve the Diagnostic Accuracy of Preoperative MRI for Uterine Leiomyosarcoma
Gigin Lin 1 , Yu-Ting Huang 1 , Koon-Kwan Ng 1 , and Shu-Hang Ng 1
1
Department of Medical Imaging and
Intervention, Chang Gung Memorial Hospital and Institute
for Radio, Chang Gung Memorial Hospital and Chang Gung
University, Linkou, Taoyuan, Taiwan
This study is designed to assess the impact of
gadolinium contrast administration on magnetic resonance
(MR) in pre-operative diagnosis of uterine
leiomyosarcoma (LMS). The central non-enhancing area (CNE)
was identified as a MR characteristic for LMS, with an
area under the receiver operating characteristic (ROC)
curve (AUC) of 0.98, which was significantly greater
than that of T1WI (AUC = 0.67, p < 0.01), T2WI (AUC =
0.65, p < 0.001) or DWI (AUC = 0.69, p < 0.001). CNE is
an MR characteristic for LMS thus intravenous contrast
medium administration is important for preoperative
diagnosis of LMS.
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