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Abstract #1552

Importance of Intravenous Contrast Administration to Improve the Diagnostic Accuracy of Preoperative MRI for Uterine Leiomyosarcoma

Gigin Lin 1 , Yu-Ting Huang 1 , Koon-Kwan Ng 1 , and Shu-Hang Ng 1

1 Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital and Institute for Radio, Chang Gung Memorial Hospital and Chang Gung University, Linkou, Taoyuan, Taiwan

This study is designed to assess the impact of gadolinium contrast administration on magnetic resonance (MR) in pre-operative diagnosis of uterine leiomyosarcoma (LMS). The central non-enhancing area (CNE) was identified as a MR characteristic for LMS, with an area under the receiver operating characteristic (ROC) curve (AUC) of 0.98, which was significantly greater than that of T1WI (AUC = 0.67, p < 0.01), T2WI (AUC = 0.65, p < 0.001) or DWI (AUC = 0.69, p < 0.001). CNE is an MR characteristic for LMS thus intravenous contrast medium administration is important for preoperative diagnosis of LMS.

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