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Abstract #1561

Assessment of renal blood flow and oxygenation in clear cell renal cell carcinomas using MRI

Han-Mei Zhang 1 , Xiao Lv 2 , Pan-Li Zuo 3 , Niels Oesingmann 4 , and Bin Song 1

1 Department of radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China, 2 Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China, 3 Siemens Healthcare, MR Collaborations NE Asia, Beijing, China, 4 Siemens HC, New York State, United States

In order to reduce the risk of contrast material induced nephropathy by contrast-enhancement computed tomography and nephrogenic systemic fibrosis with renal insufficiency by contrast-enhancement magnetic resonance imaging have been of increasing concern, this study aimed to assess the performance of two noninvasive functional MRI methods, arterial spin-labeling (ASL) and blood oxygenation level dependent (BOLD) imaging, in characterizing the blood flow and oxygenation level of clear cell RCC.The results showed blood flow measured by ASL and oxygenation level by BOLD had significant differences between entire tumor and ipsilateral/contralateral renal cortex.

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