Abstract #1563
Non-invasive Assessment of the whole kidney by MOLLI T1 Mapping in chronic kidney disease patients
Iris Friedli 1 , Lindsey Alexandra Crowe 1 , Lena Berchtold 2 , Solange Moll 3 , Karine Hadaya 4 , Pierre-Yves Martin 4 , Sophie De Seigneux 4 , and Jean-Paul Valle 1
1
Division of Radiology, Faculty of Medicine,
Geneva University Hospital, University of Geneva,
Geneva, Switzerland,
2
Division
of Internal Medicine, Faculty of Medicine, Geneva
University Hospital, University of Geneva, Geneva,
Switzerland,
3
Division
of Pathology, Faculty of Medicine, Geneva University
Hospital, University of Geneva, Geneva, Switzerland,
4
Division
of Nephrology, Faculty of Medicine, Geneva University
Hospital, University of Geneva, Geneva, Switzerland
There is an important need of non-invasive biomarkers to
monitor, in situ, the chronic kidney disease (CKD)
evolution. In this study, we investigated a free
breathing Modified Look-Locker Inversion Recovery
(MOLLI) motion corrected T1 mapping sequence in CKD
patients to enable the difference between healthy
volunteers and CKD patients. High image quality was
obtained in all the patients. A highly significant
difference in the mean T1 was revealed between the
cortex but not the medulla of healthy volunteers and
patients. This study justifies further clinical studies
on the use of MOLLI T1 mapping in kidney patients.
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