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Abstract #1565

Comprehensive Assessment of Renal BOLD MRI using Multiple Moment Analysis: Application to Subjects with CKD

Jon Thacker 1 , Lu-Ping Li 2,3 , Wei Li 2,3 , Stuart Sprague 2,3 , and Pottumarthi Prasad 2,3

1 Northwestern University, Chicago, Illinois, United States, 2 NorthShore University HealthSystem, Illinois, United States, 3 University of Chicago, Illinois, United States

The purpose of this study was to evaluate a renal blood oxygenation level-dependent (BOLD) MRI analysis technique utilizing the entire renal parenchyma based on multiple moments of the R2* distribution. Multiple moment analysis is able to detect changes in subjects between baseline and following furosemide, as well as between control and CKD groups. This method may allow for a more robust analysis of R2* maps as compared to conventional ROI analysis in addition to minimizing observer subjectivity in analyzing renal BOLD data.

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