Abstract #1565
Comprehensive Assessment of Renal BOLD MRI using Multiple Moment Analysis: Application to Subjects with CKD
Jon Thacker 1 , Lu-Ping Li 2,3 , Wei Li 2,3 , Stuart Sprague 2,3 , and Pottumarthi Prasad 2,3
1
Northwestern University, Chicago, Illinois,
United States,
2
NorthShore
University HealthSystem, Illinois, United States,
3
University
of Chicago, Illinois, United States
The purpose of this study was to evaluate a renal blood
oxygenation level-dependent (BOLD) MRI analysis
technique utilizing the entire renal parenchyma based on
multiple moments of the R2* distribution. Multiple
moment analysis is able to detect changes in subjects
between baseline and following furosemide, as well as
between control and CKD groups. This method may allow
for a more robust analysis of R2* maps as compared to
conventional ROI analysis in addition to minimizing
observer subjectivity in analyzing renal BOLD data.
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