Abstract #1578
Quantification and reproducibility of single kidney function using DCE-MRI in healthy subjects
Eli Eikefjord 1,2 , Erling Andersen 3 , Jan Ankar Monssen 1 , Erlend Hodneland 4 , Erik Hanson 5 , Arvid Lundervold 1,4 , and Jarle Rrvik 1,2
1
Radiology, Haukeland University Hospital,
Bergen, Hordaland, Norway,
2
Clinical
Medicine, University of Bergen, Bergen, Hordaland,
Norway,
3
Clinical
Engineering, Haukeland University Hospital, Bergen,
Hordaland, Norway,
4
Biomedicine,
University of Bergen, Hordaland, Norway,
5
Mathematics,
University of Bergen, Hordaland, Norway
Documentation on reproducibilities in estimation of
renal functional parameters using DCE-MRI is limited.
Twenty healthy subjects being in a controlled
physiological state were examined twice with identical
3D SPGR DCE-MRI acquisition technique, aiming at
exploring intra-subject reproducibility and variability
in perfusion and filtration estimates. Within-subject
variation was 14-24% and estimates were reproduced with
good to excellent agreement between MR1 and MR2. Mean
difference in total GFR and renal blood flow between MR1
and MR2 was 3.5 ml/min and 43.7 ml/100ml/min,
respectively. Variance and agreement correspond to
expected levels accounting for normal physiological
variation and instances of quality impaired exams.
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