Abstract #1587
Radioembolization dosimetry using gadoxetate disodium for segmentation of the healthy liver parenchyma
Hanke J Schalkx 1 , Jip P Prince 1 , Gerrit H van de Maat 2 , Peter R Seevinck 3 , Clemens Bos 3 , Wouter B Veldhuis 1 , Maarten S van Leeuwen 1 , Maurice AAJ van den Bosch 1 , Marnix GEH Lam 1 , and Marijn van Stralen 3
1
Radiology and Nuclear Medicine, University
Medical Center Utrecht, Utrecht, Utrecht, Netherlands,
2
Quirem
Medical BV, Diepenveen, Netherlands,
3
Image
Sciences Institute, University Medical Center Utrecht,
Utrecht, Utrecht, Netherlands
In intra-arterial radioembolization for the treatment of
non-resectable liver cancer, the amount of injected
activity is limited by its effect on the healthy
parenchyma. Therefore, it is essential that the healthy
parenchymal volume is measured accurately. In a
holmium-treated patient population, the role of
gadoxetate-enhanced MRI was investigated. Automatic
segmentation of the liver parenchyma without hypointense
tumors and vessels was feasible. Gadoxetate-based
automatic segmentation of the nontumorous hepatic
parenchyma could benefit radioembolization dosimetry and
dosimetry-based treatment planning.
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