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Abstract #1615

Abdominal diffusion imaging parameters from free-breathing multiple-averaged and finely-sampled decay curves compared to acquisition using active breathing control

Neil Peter Jerome 1 , Evangelia Kaza 1 , Matthew R Orton 1 , James A d'Arcy 1 , Bernd Kuehn 2 , Dow-Mu Koh 3 , David J Collins 1 , and Martin O Leach 1

1 Radiotherapy & Imaging, The Institute of Cancer Research, Sutton, London, United Kingdom, 2 Healthcare, Siemens AG, Erlangen, Germany, 3 Department of Radiology, Royal Marsden Hospital, Sutton, United Kingdom

The blurring from respiratory motion found in free-breathing abdominal diffusion imaging can be difficult to resolve without impacting patient comfort. Sufficient sampling of the diffusion curve may alleviate the need for prospective motion control; though the form of the optimal sampling scheme must reflect the question being asked. We compare diffusion parameters from two alternate free-breathing schemes (32 b-values with no averaging, and 9 b-values with 4 averages) against a 32 b-value sequence acquired under active breathing control, and show lack of significant differences, indicating intended choice of post-processing may be an important consideration in designing abdominal DWI protocols.

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