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Abstract #1632

Detecting signal changes in heated bone with a 3D spiral ultra-short echo time sequence

Samuel Fielden 1 , John Mugler, III 2 , Wilson Miller 2 , Kim Butts Pauly 3 , and Craig Meyer 1,2

1 Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States, 2 Radiology, University of Virginia, Charlottesville, Virginia, United States, 3 Radiology, Stanford University, Palo Alto, California, United States

Monitoring bone heating during focused ultrasound procedures is desirable. The popular PRF shift technique for MR thermometry cannot be performed in bone due to its short T2. However, T1 and T2 are temperature dependent, and so an alternative method is to use signal intensity changes, detected by ultra-short echo time (UTE) sequences, as a method by which bone thermometry can be performed. Here, we have used a rapid 3D spiral UTE sequence to image a heated bone sample as it cools down in the bore of the MRI and have detected signal intensity changes consistent with T1-lengthening of heated tissue.

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