A simple method (eMoS) for T1 mapping is more accurate and robust than the Variable Flip Angle (VFA) method

The purpose of this work is to present a simplified method (eMoS) that can be used to compute T1 maps from two low flip angle SPGR signal acquisitions if B1 maps are known. A study of the effects of B1 errors and noise on eMoS in contrast to the effect of these on the standard variable flip angle (VFA) method can be used to explain the observed differences in human brain, in vivo, T1 maps. Simulations and human scans are used to demonstrate the improved accuracy and noise robustness of the eMoS relative to the VFA method for T1 mapping.

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