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Abstract #1675

Whole-Brain Multi-Parameter mapping using Dictionary learning

Sampada Bhave 1 , Sajan Goud Lingala 2 , Casey P Johnson 1 , Vincent A Magnotta 1 , and Mathews Jacob 1

1 University of Iowa, Iowa City, Iowa, United States, 2 Electrical Engineering, University of Southern California, Los Angeles, California, United States

Quantification of multiple tissue parameters is emerging as a powerful tool in diagnosing various neurological and psychiatric diseases. However the major bottleneck in its routine clinical use is the long acquisition time. In addition, long acquisition times are likely to result in motion induced artifacts. In this work, we propose a dictionary learning based scheme to simultaneously recover T1ρ and T2 maps. The proposed method models the data as a weighted linear combination of basis functions from a dictionary, which is learned from the measured data.

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