Inversion Group (IG) Fitting: A New Fitting Algorithm for Modified Look-Locker Inversion Recovery (MOLLI) that allows for Arbitrary Inversion Groupings
Issac Y Yang 1 , Kai-Ho Fok 1 , Bernd J Wintersperger 2,3 , and Marshall S Sussman 2,3
Faculty of Medicine, University of Toronto,
Toronto, Ontario, Canada,
of Medical Imaging, University of Toronto, Toronto,
Department of Medican Imaging, University Health Network
& Mt. Sinai Hospital, Toronto, Ontario, Canada
Modified Look-Locker Inversion Recovery (MOLLI) is a
common technique for T1 mapping of the heart. However,
it requires a lengthy rest period in between inversion
groupings to allow for complete magnetization recovery.
A new MOLLI fitting algorithm with a new fitting model
is presented in this work to allow for arbitrary
inversion groupings and rest periods, including no rest
period. Phantom and in-vivo experiments verified the
technique. T1 values measured using several different
inversion grouping/rest period combinations yielded
consistent results with the new algorithm, but with a
slight loss of precision.
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