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Abstract #1688

Comparison of Indirect and Stimulated Echo Compensated T2 Relaxometry Techniques: Extended Phase Graph vs Shinnar-Le Roux Based Modelling

Kelly C McPhee 1 and Alan H Wilman 2

1 Physics, University of Alberta, Edmonton, Alberta, Canada, 2 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada

Recent works have implemented methods to fit for single component T2 from slice selective multi-echo spin echo experiments with indirect and stimulated echo compensation. These works have made use of either the Extended Phase Graph with Fourier Transform slice approximations, or Shinnar-Le Roux and Bloch simulations to model complete echo pathways. Here, we compare the recently demonstrated SLR based fitting technique with prior flip angle measurement to the EPG based method which is a commonly used correction technique for multi-echo spin echo based T2 measurements. We use simulations and human in vivo experiments to compare these two methods of indirect and stimulate echo compensated T2 fitting.

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