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Abstract #1710

Rapid phase imaging with 3D echo-planar imaging (EPI) for quantitative MRI A simulation study on image artifacts

Paul Polak 1 , Robert Zivadinov 1,2 , and Ferdinand Schweser 1,2

1 Department of Neurology, Buffalo Neuroimaging Analysis Center, State University of New York at Buffalo, Buffalo, NY, United States, 2 Molecular and Translational Imaging Center, MRI Center, Clincal and Translational Research Center, Buffalo, NY, United States

Gradient echo (GRE) imaging has received increased attention because of the GRE signal's effectiveness in elucidating information about magnetic tissue properties and microscopic tissue architecture. However, multi-echo GRE sequences are hindered by their lengthy acquisition times. Multi-shot GRE 3D echo-planar imaging (EPI) attempts to circumvent this problem by acquiring multiple k -space lines per shot but what effect these acquisition strategies have on the underlying magnitude and phase components is not clear. In this work we systematically investigate the effect of magnitude signal decay and phase evolution during the readout on the accuracy of complex-valued GRE signals measured with simulated segmented 3D EPI sequences.

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