RF instrumentation for same-breath triple-nuclear lung MR imaging of 1 H and hyperpolarized 3 He and 129 Xe at 1.5T

The hyperpolarized gases, ³ He and ¹²⁹ Xe have distinct properties, and provide unique and complementary functional information from the lungs. A double/triple-nuclear same-breath imaging exam of the lungs with ¹ H, ³ He and ¹²⁹ Xe can therefore provide exclusive functional information from each of the gas images and complementary co-registered structural information from ¹ H images in the same physiological time frame. This study describes the development of a RF instrumentation for same-breath triple-nuclear ( ³ He- ¹²⁹ Xe- ¹ H) MR imaging. Application to same-breath ventilation ( ³ He- ¹²⁹ Xe- ¹ H) imaging and same-breath ³ He- ¹²⁹ Xe diffusion imaging are demonstrated.

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