Abstract #1812
RF instrumentation for same-breath triple-nuclear lung MR imaging of 1 H and hyperpolarized 3 He and 129 Xe at 1.5T
Madhwesha Rao 1 , Juan Parra-Robles 1 , Helen Marshall 1 , Neil Stewart 1 , Guilhem Collier 1 , and Jim Wild 1
1
University of Sheffield, Sheffield, South
Yorkshire, United Kingdom
The hyperpolarized gases,
3
He
and
129
Xe
have distinct properties, and provide unique and
complementary functional information from the lungs. A
double/triple-nuclear same-breath imaging exam of the
lungs with
1
H,
3
He
and
129
Xe
can therefore provide exclusive functional information
from each of the gas images and complementary
co-registered structural information from
1
H
images in the same physiological time frame. This study
describes the development of a RF instrumentation for
same-breath triple-nuclear (
3
He-
129
Xe-
1
H)
MR imaging. Application to same-breath ventilation (
3
He-
129
Xe-
1
H)
imaging and same-breath
3
He-
129
Xe
diffusion imaging are demonstrated.
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