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Abstract #1827

Incorporation of TOF information reduces artifacts in simultaneous TOF PET/MR scanning

Edwin G.W. ter Voert 1 , Helen Davison 1,2 , Felipe de Galiza Barbosa 1,3 , Martin Huellner 1,4 , Patrick Veit-Haibach 1,3 , and Gaspar Delso 5

1 Department of Medical Imaging, Division of Nuclear Medicine, University Hospital Zurich, Zurich, Zurich, Switzerland, 2 Department of Medical Physics, Royal United Hospitals Bath NHS Foundation Trust, Bath, Somerset, United Kingdom, 3 Department of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Zurich, Switzerland, 4 Department of Medical Imaging, Clinic of Neuroradiology, University Hospital Zurich, Zurich, Zurich, Switzerland, 5 GE Healthcare, Waukesha, WI, United States

MR based attenuation correction (MR-AC) is still challenging in simultaneous PET/MR scanning; especially near metal implants. A possible solution could be the inclusion of time-of-flight (TOF) information into the PET image reconstruction algorithm. To evaluate the influence of TOF on artifact reduction and improvement in PET image quality, 35 patients were included and scheduled for a comparative scan in a new simultaneous TOF PET/MR scanner. A total 46 clinical PET image artifacts and 21 simulated artifacts were being evaluated. In conclusion, time-of-flight information in simultaneous TOF PET/MR scanning significantly (p<0.01) reduces PET artifacts and improves clinical reader confidence.

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