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Abstract #1840

Assessment of the aging human skin with a unilateral NMR scanner

Elad Bergman 1 , Yifat Sarda 1 , Noa Ritz 2 , Edmond Sabo 2 , Reuven Bergman 2 , and Uri Nevo 1

1 Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel, Israel, 2 Departments of Dermatology and Pathology, Rambam Health Care Campus and The Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel, Israel

We present a method for evaluation of skin aging and of sun damage with a unilateral stray-field NMR scanner operating in low field. In-vivo profiles with relaxation times of the sun-protected and sun-exposed forearm skins were measured in 9 female subjects. Biopsies were used as references. A significant increase in the fraction of the slow T_2 component, and in the value of the T_(2 )component itself correlated with chronological aging. A further increase was superimposed in the sun-exposed forearm. The results suggest that this affordable hardware, so far not used clinically, can serve as a tool for skin aging assessment.

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