Meeting Banner
Abstract #1868

Improved MR thermometry in the presence of non-water proton signals

Jacco A de Zwart 1 , Peter van Gelderen 1 , Qi Duan 1 , Natalia Gudino 1 , Cem M Deniz 2 , Leeor Alon 2 , and Jeff H Duyn 1

1 Advanced MRI, LFMI, NINDS, National Institutes of Health, Bethesda, MD, United States, 2 Dept. of Radiology & Sackler Institute of Graduate Biomedical Sciences, NYU School of Medicine, New York, NY, United States

A non-linear least squares fitting based method for MR thermometry is proposed and developed for coil performance and RF-safety assessment using recently developed sucrose-doped agarose-water phantoms. The method, which acquires a minimum of four gradient-echo signals, allows reliable measurement of RF-heating-related shifts in water proton resonance frequency (PRF) in the presence of confounding proton signals from the doping material. Calibration experiments show water-PRF temperature dependence of -0.009 ppmK -1 for these agarose-based phantoms, similar to literature values for tissue (~-0.01 ppmK -1 ). However, otherwise identical gelatin-based gels show reduced water-PRF temperature dependence (-0.006 ppmK -1 ), possibly due to spin exchange.

This abstract and the presentation materials are available to members only; a login is required.

Join Here