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Abstract #1969

Simple method for automatic frequency and phase alignment of in-vivo MR spectra

Evita C. Wiegers 1 , Bart Philips 1 , Hanne M. M. Rooijackers 2 , Alan J. Wright 3 , Arend Heerschap 1 , and Marinette van der Graaf 1,4

1 Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands, 2 Internal Medicine, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands, 3 Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom, 4 Pediatrics, Radboud University Medical Center, Nijmegen, Gelderland, Netherlands

When subtracting MRS data, which is commonly done in J-difference editing techniques, it is of great importance that spectra are accurately phase and frequency aligned with respect to each other. To allow accurate phase and frequency alignment, we present a simple, robust and fast alignment algorithm, based on maximizing the normalized scalar product between two spectra.

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