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Abstract #2050

Fast, focused fMRI at high spatial resolution: 3D-EPI-CAIPI with cylindrical excitation

Wietske van der Zwaag 1 , Mayur Narsude 2 , Marzia Restuccia 2 , Olivier Reynaud 1,3 , Daniel Gallichan 1 , and Jose P. Marques 1

1 CIBM, EPFL, Lausanne, VD, Switzerland, 2 LIFMET, EPFL, Lausanne, VD, Switzerland, 3 Department of Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, NYU School of Medicine, New York, NY, United States

The 3D-EPI-CAIPI sequence was combined with a 2D-RF pulse to selectively image a cylindrical region of interest (such as the brainstem) with high spatial (1.5mm) and high temporal resolution (1s/volume). Use of the cylindrical excitation pulse did not reduce tSNR or BOLD sensitivity within the region of interest. This sequence allows a significant reduction of the FOV compared to full slab acquisitions, which can be used to increase spatial and/or temporal resolution and to reduce susceptibility-induced distortions, finally resulting in functional data with high spatio-temporal resolution, high anatomical fidelity and high BOLD sensitivity.

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