Abstract #2054
Simultaneous Multislice Acquisition to Avoid Motion Artifacts in Challenging Patient Populations
Andrew S Nencka 1 , Andrew M Huettner 2 , L. Tugan Muftuler 3 , Kevin M. Koch 1 , and Rasmus Birn 4
1
Departments of Biophysics and Radiology,
Medical College of Wisconsin, Milwaukee, WI, United
States,
2
Department
of Biophysics, Medical College of Wisconsin, Milwaukee,
WI, United States,
3
Department
of Neurosurgery, Medical College of Wisconsin,
Milwaukee, WI, United States,
4
Department
of Psychiatry, University of Wisconsin, Madison, WI,
United States
Simultaneous multislice (SMS) imaging is becoming wide
spread in resting state acquisitions following
developments from the Human Connectome Project. While
most SMS studies are focused upon increasing both
spatial and temporal resolution, this study is focused
primarily upon increasing volume acquisition time to
effectively freeze subject motion. In cases of
challenging patient populations, including unsedated
children, subject motion can destroy functional
connectivity measures. The goal of this work is to
acquire the full brain volume as quickly as possible in
a resting state acquisition that is expected to be
corrupted by motion. In this case, intra-volume motion
artifacts can be eliminated. Although full volume
coverage with 8mm isotropic voxels can be achieved in
150 ms, data acquired over 390 ms with spatial
resolution of 2.6 x 2.6 x 4 mm
3
was
found to sufficiently avoid intra-acquisition motion
artifacts in the presence of substantial motion. This
work offers a new perspective for the application of SMS
acquisitions in patient populations.
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