Abstract #2168
Regional quantifying normal-appearing white matter perfusion in mild to moderate hypertension using 3D pseudo-continous arterial spin labeling
Ting Wang 1 , Yanhua Li 2 , Xinhong Guo 2 , Diandian Huang 1 , Lin Ma 1 , and Xin Lou 1
1
Department of Radiology, Chinese PLA General
Hospital, Beijing, Beijing, China,
2
Department
of Cardiology, Chinese PLA General Hospital, Beijing,
Beijing, China
White matter (WM) is the predilection area of lacunar
infarction in hypertensive patients. It was hypothesized
that abnormal CBF in WM appeared at early stage of
hypertension, hence, we recruited thirty hypertensive
patients and thirty healthy controls of an appropriate
age to detect their CBF modifications of
normal-appearing WM using 3D pcASL technique. As
expected, compare to healthy volunteers, CBF values in
various WM regions were observed to be lower in
hypertensive patients. This proves that 3D pCASL has
ability to detect the subtle hemodynamic abnormalities
even at the early stage of hypertension.
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