Meeting Banner
Abstract #2186

Quantification of the local dynamic of the cerebrovascular autoregulation

Marco Piccirelli 1 , Bas van Niftrik 2 , Oliver Bozinov 2 , Athina Pangalu 1 , Antonios Valavanis 1 , Luca Regli 2 , and Jorn Fierstra 2

1 Neuroradiology University Hospital, Zurich, ZH, Switzerland, 2 Neurosurgery University Hospital, Zurich, ZH, Switzerland

To quantify the local cerebrovascular autoregulation in function of the partial pressure of CO2 (PaCO2), we combined quantitative cerebral flow measurements obtained with ASL and cerebrovascular reactivity (CVR) with BOLD fMRI. To control for PaCO2, a prospective end tidal gas blender was used. This unique combination during a capnic challenge in healthy subjects and steno occlusive patients allows for the assessment of a quantitative CVR curve and deliver a multi-parametric map including cerebrovascular reactivity, reserve capacity and mean cerebral blood flow measurements during known hypocapnic and hypercapnic states.

This abstract and the presentation materials are available to members only; a login is required.

Join Here