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Abstract #2188

Susceptibility-weighted imaging of acute ischemic stroke: quantification of hypoperfusion

Hung-Wen Kao 1,2 , Yu-Chuan Chang 3 , Ching-Po Lin 2,4 , and Chien-Yuan Eddy Lin 5,6

1 Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, 2 Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 3 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 4 Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, 5 GE Healthcare, Taipei, Taiwan, 6 GE Healthcare China, Beijing, China

Susceptibility-weighted imaging (SWI) is very sensitive in detecting blood products and showing blood-oxygen-level dependent (BOLD) signal changes presumably from different concentrations of deoxygenated blood. Therefore, we hypothesize that SWI could provide oxygen metabolic information in relation to perfusion in patients with acute ischemic stroke. In our study, we compared area percentages of increased BOLD signal (IBS) in ROIs of restricted diffusion and perfusion defect. The results suggested a positive correlation between perfusion and IBS, a finding contradicting the implication of IBS as miserable perfusion and indicating a mismatch between perfusion and oxygen metabolism.

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