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Abstract #2262

Computer Aided Radiological Diagnostics: Random Forest Classification of Glioma Tumor Progression using Image Texture Parameters derived from ADC-Maps.

Johannes Slotboom 1 , Nuno Pedrosa de Barros 1 , Stefan Bauer 2 , Urspeter Knecht 1 , Nicole Porz 3 , Philippe Schucht 3 , Pica Pica 4 , Andreas Raabe 3 , Roland Wiest 5 , and Beate Sick 6

1 DRNN, Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Bern, Switzerland, 2 Institute of Surgical Technology and Biomechanics, University Bern, Bern, Switzerland, 3 DKNS-Neurosurgery, University Hospital Bern, Bern, Switzerland, 4 DOLS-Radiooncology, University Hospital Bern, Bern, Switzerland, 5 1DRNN, Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Bern, Switzerland, 6 Division of Biostatistics, ISPM, University Zrich, Zrich, Switzerland

Despite the huge amount of information provided by an MR-examination, the initial diagnosis and grading of frequently extremely heterogeneous brain tumors by visual inspection remains a difficult task. A diagnostic text often lists a number of most likely diagnoses, e.g. anaplastic astrocytoma or glioblastoma multiforme. Here we discuss a method for computer aided radiologic diagnostics on how texture parameter analysis in combination with the advanced statistical classification random forest algorithm can be used to solve important differential diagnosis problem for individual diagnostics.

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