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Abstract #2325

Arterial Spin Labeling Improvement by Incorporating Local Similarity with Anatomic Images

Li Zhao 1 , Weiying Dai 1 , and David Alsop 1

1 Radiology, Beth Israel Deaconess Medical Center & Harvard Medical School, Boston, MA, United States

Arterial spin labeling provides important perfusion information, but it suffers from intrinsically low SNR and spatial resolution. Since high quality T1 weighted images are collected in routine MRI procedures, we present a method to enhance ASL image by incorporating its local similarity with anatomic images. The proposed method was evaluated on five tumor patients and results preserved the low resolution contrast of ASL with improved CNR and spatial resolution.

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