Statistical mapping of cerebral blood flow territories using multi-phase pseudo-continuous arterial spin labeling

Depicting the primary flow territories of the brain is of clinical importance because collateral circulation is a common finding in patients with steno-occlusive disease. In this study, we proposed to generate statistical mapping of the flow territories of the left/right internal carotid arteries and vertebral arteries by using multi-phase vessel-encoded pseudocontinuous arterial spin labeling and the general linear model. The described method allows comparison between flow territories and/or subject populations to be carried out in a statistical framework similar to that in functional MR imaging.

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