B1 mapping of the breast with a reference tissue method

Accurate measurements of the B1 field are critical in DCEMRI of the breast as small errors in the flip angle can lead to significant bias in measurements of T1, contrast media concentration, and pharmacokinetic parameters. We present a novel method for mapping the B1 field across the breast. This method is based on the fact that the T1 of fat in the breast can be accurately measured and has very low inter/intra-patient variability. The reference T1 in each image voxel is used to calculate local B1. Then the full B1 map is estimated. These maps were used to produce improved estimates of native T1

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