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Abstract #2389

Off-resonance compensated velocity selective RF pulse design for reducing signal dropout in vessel wall imaging

Yunduo Li 1 , Shuo Chen 1 , Zechen Zhou 1 , Rui Li 1 , and Chun Yuan 1,2

1 Center for Biomedical Imaging Research, Beijing, Beijing, China, 2 Department of Radiology, University of Washington, Seattle, Washington, United States

In this study, we improved the design of velocity-selective RF pulse to compensate signal dropout due to off-resonance effect and evaluated its feasibility in carotid vessel wall imaging. Simulation and in-vivo studies showed that the new VS pulse can partially compensate the signal dropout in static tissue, which results in better image quality and contrast. As improved VS pulse widened the pass band of VS profile, which sacrificed blood suppression efficiency in case of slow blood flow causing image artifacts (Fig.4). A trade-off between off-resonance compensation and blood suppression efficiency should be considered to relief off-resonance with efficient blood suppression.

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