Fully-refocused SPatio-temporal ENcoding (SPEN) MRSI using Fourier-Encoding Polychromatic Spectral Pulses

Fully refocused SPatiotemporal ENcoding (SPEN) imaging has recently been shown to provide a robust alternative to EPI erasing T ₂ * and chemical-shift effects from a single-scan image. Despite this cancelling of shift effects, we show how utilizing a polychromatic refocusing pulse can lead to a Fourier-encoded fully refocused SPEN sequence which can map chemical shifts with high temporal efficiency while maintaining the robustness of fully-refocused SPEN. These SPEN spectroscopic images are decoded by a Fourier transform procedure into resonance-specific images. The usefulness of this PC-SPEN approach is demonstrated on a metabolite phantom and in vivo water-fat separation imaging at 7 T.

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