Fully-refocused SPatio-temporal ENcoding (SPEN) MRSI using Fourier-Encoding Polychromatic Spectral Pulses
Zhiyong Zhang 1,2 and Lucio Frydman 1
Chemical Physics Department, Weizmann
Institute of Science, Rehovot, Israel,
of Electronic Science, Xiamen University, Xiamen,
Fully refocused SPatiotemporal ENcoding (SPEN) imaging
has recently been shown to provide a robust alternative
to EPI erasing T
* and chemical-shift
effects from a single-scan image. Despite this
cancelling of shift effects, we show how utilizing a
polychromatic refocusing pulse can lead to a
Fourier-encoded fully refocused SPEN sequence which can
map chemical shifts with high temporal efficiency while
maintaining the robustness of fully-refocused SPEN.
These SPEN spectroscopic images are decoded by a Fourier
transform procedure into resonance-specific images. The
usefulness of this PC-SPEN approach is demonstrated on a
metabolite phantom and
separation imaging at 7 T.
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