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Abstract #2399

SLR Pulse Implementation in Multi-Slice 2D FLASH Pulse Sequence for 3T MRI and Beyond

A Alhamud 1 , Jay Moore 2 , Neal Derman 1 , Ernesta Meintjes 1 , and Marcin Jankiewicz 1

1 Human Biology,MRC/UCT Medical Imaging Research Unit, University of Cape Town, Cape Town, Western Cape, South Africa, 2 Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States

Excitation part of 2D FLASH multi-slice sequence is replaced by a train of slice-selective SLR-pulses with built-in |B 1 + |-insensitivity. Performance of the re-designed sequence, measured in SNR gain over sequence with a standard excitation waveform, is verified in-vivo experiment in human head at 3 Tesla. The gain is substantial (up to 60% more SNR is observed) in inhomogeneity-challenged areas even when slice-profile of the standard waveform favors it over the optimized alternative . This modification to FLASH sequence represents a simple way in which image quality can be improved in various MR modalities (including fMRI, DTI and spectroscopy) in case where quality is corrupted byRF and static field inhomogeneities.

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