Abstract #2399
SLR Pulse Implementation in Multi-Slice 2D FLASH Pulse Sequence for 3T MRI and Beyond
A Alhamud 1 , Jay Moore 2 , Neal Derman 1 , Ernesta Meintjes 1 , and Marcin Jankiewicz 1
1
Human Biology,MRC/UCT Medical Imaging
Research Unit, University of Cape Town, Cape Town,
Western Cape, South Africa,
2
Institute
of Imaging Science, Vanderbilt University, Nashville,
TN, United States
Excitation part of 2D FLASH multi-slice sequence is
replaced by a train of slice-selective SLR-pulses with
built-in |B
1
+
|-insensitivity.
Performance of the re-designed sequence, measured in SNR
gain over sequence with a standard excitation waveform,
is verified in-vivo experiment in human head at 3 Tesla.
The gain is substantial (up to 60% more SNR is observed)
in inhomogeneity-challenged areas even when
slice-profile of the standard waveform favors it over
the optimized alternative . This modification to FLASH
sequence represents a simple way in which image quality
can be improved in various MR modalities (including
fMRI, DTI and spectroscopy) in case where quality is
corrupted byRF and static field inhomogeneities.
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