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Abstract #2446

In-vivo brain fast Rosette Spectroscopic Imaging (RSI) with reduced gradient demands/improved patient comfort and a processing pipeline with automated LCModel quantification, for all acquired voxels

Claudiu Schirda 1 , Tiejun Zhao 2 , Ovidiu Andronesi 3 , James Mountz 1 , Fernando Boada 1 , and Hoby Hetherington 1

1 Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States, 2 Siemens Medical Solutions, Pittsburgh, PA, United States, 3 Radiology, Massachusetts General Hospital, Boston, MA, United States

The rosette trajectory design flexibility is used to decrease the demands on scanner gradient system for the Rosette Spectroscopic Imaging (RSI) sequence. The reduced gradient readout strength and slew rate results (in addition to decreased Eddy currents and decreased frequency drift) in decreased acoustic noise and decreased scanner vibrations, which improves patient comfort. A 2D RSI acquisition with in-plane resolution of 8mm and a 20x20x12 3D RSI acquisition with nominal isotropic resolution of 8mm and effective voxel size of 0.55cc are demonstrated in-vivo with slew rate of 45mT/m/ms and gradient of 5.8mT/m in 32 sec and 5-10 mins, respectively.

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