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Abstract #2470

Spatial localization of relaxation dispersion by field-cycling with one-dimensional projection

Kerrin J Pine 1 , Gareth R Davies 1 , and David J Lurie 1

1 Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, United Kingdom

In field-cycling MRI, the normally stable main magnetic field B 0 is manipulated during an examination to explore the field strength dependency of relaxation rate. Clinical adoption relies on finding alternatives to T 1 dispersion imaging which is associated with lengthy scan times. A pulse sequence is described for rapid measurement of T 1 dispersion with one-dimensional projection. Results are presented demonstrating the 1D spatial variation of dispersion in a phantom. The sequence could be used to rapidly locate pathology of known dispersion for further inspection by other methods.

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