Abstract #2482
            Semi-automatic Prostate Segmentation via a Hidden Markov Model with Anatomical and Textural Priors
                      Christian Scharfenberger                     1                    , Dorothy Lui                     1                    , 						Farzad Khalvati                     2                    , Alexander Wong                     1                    , 						and Masoom Haider                     2,3          
            
            1
           
           Systems Design Engineering, University of 
						Waterloo, Waterloo, Ontario, Canada,
           
            2
           
           Department 
						of Medical Imaging, University of Toronto, Toronto, 
						Ontario, Canada,
           
            3
           
           Sunnybrook 
						Health Sciences Centre, Toronto, Ontario, Canada
          
            
          The contouring and segmentation of the prostate gland is 
						an important task in computer-aided prostate cancer 
						screening using MRI. To assist medical professionals 
						with the segmentation process, we propose a novel 
						user-guided approach to prostate segmentation in MR 
						images. The approach optimizes the energy components of 
						a modified Decoupled Active Contour framework based on a 
						Hidden Markov Model and a Rician likelihood to 
						explicitly consider user guidance and textural and 
						anatomical priors. Extensive experiments based on 10 
						patient cases and a variety of evaluation metrics showed 
						that our approach provides a significant improvement 
						over an existing semi-automatic segmentation approach.
         
 
            
				
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