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Abstract #2517

Estimation of Abdominal Aortic Aneurysm Stiffness using MR Elastography: Is Stiffness Superior to Diameter?

Shantanu Warhadpande 1 , William Kenyhercz 2 , Priyanka Illapani 2 , Brian Raterman 3 , Joshua Dowell 3 , Michael Go 3 , Patrick Vaccaro 3 , Jean Starr 3 , Richard White 3 , and Arunark Kolipaka 3

1 The Ohio State University College of Medicine, Columbus, OH, United States, 2 The Ohio State University, Columbus, OH, United States, 3 The Ohio State University Wexner Medical Center, OH, United States

It is known that changes in Abdominal Aortic Aneurysms (AAA) wall stiffness (WS) can reflect extra-cellular matrix integrity, a key factor in the pathophysiological development of AAA and the risk for rupture. Therefore, our study applied Magnetic Resonance Elastography (MRE) to determine aortic WS in 10 AAA patients. Our hypothesis was that there would be no relationship between aortic WS and AAA diameter and our results supported the hypothesis with a poor linear correlation of R2 =0.0051. In the future, a more personalized approach to AAA management using MRE-derived WS might be warranted to better assess the risk for rupture.

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