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Abstract #2519

Consistent SNR Measures for Magnetic Resonance Elastography

Armando Manduca 1 , David S Lake 1 , Khang T Huynh 1 , Rehman S Eon 1 , Elizabeth M Annoni 1 , and Richard L Ehman 1

1 Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States

In magnetic resonance elastography, the calculated stiffness values are affected by noise, which is amplified by the inversion process. It would be useful in practice to establish that, beyond some SNR threshold, stiffness calculations are accurate within some confidence limit. A variety of SNR measures have been proposed for MRE, including variations of displacement SNR and octahedral shear strain SNR. We demonstrate here that the proper SNR measure depends on the inversion algorithm used, and, more precisely, on the order of derivatives in the inversion process, and show that Laplacian-based SNR measures are required for commonly used Helmholtz inversions.

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