Abstract #2527
A small animal MR Elastography setup to study skeletal muscle damage and the etiology of pressure ulcers and related deep tissue injury.
Jules Nelissen 1,2 , Larry de Graaf 1 , Tom Schreurs 1,2 , Willeke Traa 3 , Kevin Moerman 4 , Cees Oomens 3 , Aart Nederveen 4 , Klaas Nicolay 1 , and Gustav Strijkers 1,2
1
Biomedical NMR, Department of Biomedical
Engineering, Eindhoven University of Technology,
Eindhoven, Netherlands,
2
Biomedical
Engineering and Physics, Academic Medical Center,
Amsterdam, Netherlands,
3
Soft
Tissue Biomechanics and Engineering, Department of
Biomedical Engineering, Eindhoven University of
Technology, Eindhoven, Netherlands,
4
Department
of Radiology, Academic Medical Center, Amsterdam,
Netherlands
In order to study the role of tissue mechanical
properties with MR Elastography (MRE) in the etiology of
pressure ulcer related deep tissue injury a MRE actuator
was added to a previously proposed MR compatible
indentation setup for sustained tibialis anterior (TA)
muscle loading in rats. We expect that the use of this
novel device will provide new insights in the etiology
of pressure ulcer related deep tissue injury.
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