Meeting Banner
Abstract #2529

Validation of Waveguide Magnetic Resonance Elastography Using Finite Element Model Simulation

Ria Mazumder 1,2 , Renee Miller 3 , Haodan Jiang 4 , Bradley D. Clymer 1 , Richard D. White 2,5 , Alistair Young 3 , Anthony Romano 6 , and Arunark Kolipaka 2,5

1 Department of Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States, 2 Department of Radiology, The Ohio State University College of Medicine, Columbus, OH, United States, 3 Department of Anatomy with Radiology, The University of Auckland, New Zealand, 4 Department of Research and Development, Ohio Supercomputer Center, OH, United States, 5 Department of Internal Medicine-Division of Cardiology, The Ohio State University College of Medicine, OH, United States, 6 Naval Research Laboratory, DC, United States

Anisotropic mechanical properties of tissues vary in response to different pathological conditions; hence, the development of a technique for non-invasive anisotropic stiffness quantification is expected to have diagnostic and prognostic significance. Recently, waveguide magnetic resonance elastography (MRE) has been used to non-invasively estimate anisotropic stiffness of biological tissues by measuring tissue deformation as a result of external perturbation in directions specified by fiber orientation. In this study, we simulate fibers using finite element modeling in a cylindrical rod to validate the stiffness measurements obtained using waveguide MRE. Our results show that the technique can successfully estimate anisotropic stiffness in an orthotropic material.

This abstract and the presentation materials are available to members only; a login is required.

Join Here