Abstract #2566
Comparison of breath-holding and respiratory gating T2* mapping in the heart and liver for thalassemia major patients
Xiaodong Chen 1,2 , Zuoquan Zhang 3 , Qihua Yang 1 , Zebin Luo 2 , Ziliang Cheng 1 , Jiaji Mao 1 , Queenie Chan 4 , Hua Guo 5 , and Biling Liang 1
1
Sun Yat-Sen Memorial Hospital, Guangzhou,
Guangdong, China,
2
Affiliated
hospital of Guangdong Medical College, Zhanjiang,
Guangdong, China,
3
The
Fifth Affiliated Hospital of Sun Yat-Sen University,
Guangdong, China,
4
Philips
Healthcare, Hong Kong, China,
5
Center
for Biomedical Imaging Research, Department of
Biomedical Engineering, School of Medicine, Tsinghua
University, Beijing, China
With the development of MRI techniques, T2* mapping is
becoming the routine examination for evaluation of the
iron level of the heart and liver in TM patients.
Generally, the common T2* sequence is scanned with one
breath hold and less attention is paid to motion
artifact reduction because most adults can suspend
respiration on command. However, as the recommended age
to start the first cardiac MRI screening in TM patients
has become younger, more and more children with TM will
get T2* examination and most of them are generally less
able to suspend respiration. In this study, We optimized
a technique of T2* respiratory gating, developed and
tested the use of respiratory gating to decrease motion
artifacts in pediatric heart and liver T2* MRI
examinations. From the preliminary study it suggests
that, comparing to the results of breath-hold T2*
scanning, the accuracy and reproducibility of
respiratory gating method are good enough to be used in
the clinical practice.
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