3D Dynamic T1 Mapping of the Myocardium Using a Time-Varying Subspace

T1 mapping of the myocardium shows great promise for quantitative characterization of myocardial tissue. The partial separability (PS) model has previously been shown to be effective for reducing the data acquisition requirements of static parameter mapping; here we extend the model to accelerate variable-flip-angle dynamic 3D T1 mapping using a time-varying subspace (or tensor-product subspace). We have successfully applied the proposed method to significantly accelerate variable-flip-angle dynamic 3D T1 mapping for diagnosis of ischemic reperfusion injury in rats.

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