Preliminary Rat Myocardial Tissue Characterisation at 4.7T
Matthew Firth 1 , Marco Mingarelli 1 , Hugh Seton 1 , and Dana Dawson 1
University of Aberdeen, Aberdeen, United
In-vivo MRI was carried out on four healthy rats at 4.7
T to obtain a series of T2* measurements in the heart
septum. A prospectively gated gradient echo pulse
sequence was used with TE values covering the range 5-30
ms. The results were combined to provide a normal
dataset for future comparison with rat studies of iron
overload cardiomyopathy or cardiac contrast agents. The
mean T2* value was 10.12 4.40 ms. We discuss measures
that could be taken to improve SNR and reduce signal
variation in prospectively gated studies.
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