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Abstract #2640

Whole-Heart Free-Breathing Phase-Sensitive Inversion-Recovery Late Gadolinium Enhancement Imaging with High Isotropic Spatial Resolution Using Respiratory Self-Navigation: a First Patient Study

Davide Piccini 1,2 , Simone Coppo 2 , Giulia Ginami 2 , Gabriele Bonanno 2 , Tobias Rutz 3 , Gabriella Vincenti 3 , Juerg Schwitter 3 , and Matthias Stuber 2

1 Advanced Clinical Imaging Technology, Siemens Healthcare IM BM PI, Lausanne, Switzerland, 2 Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL) / Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 3 Division of Cardiology and Cardiac MR Center, University Hospital of Lausanne (CHUV), Lausanne, Switzerland

Respiratory self-navigation (SN) for whole-heart MRI provides 100% scan efficiency and increased ease of use for the operator. The SN technique was combined with a 3D radial acquisition for phase sensitive inversion recovery (3D-SN PSIR) imaging, featuring high motion and undersampling robustness. Free-breathing 3D-SN PSIR was compared to standard 2D breathhold PSIR imaging in patients with positive late gadolinium enhancement findings. Preliminary results show that free-breathing 3D-SN PSIR achieves robust nulling of healthy myocardium, while preserving high-signal in fibrotic tissue. Overall high diagnostic quality is preserved. Such high-resolution isotropic scar definition could allow for better planning of arrhythmia ablation procedures.

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