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Abstract #2646

Utility of Multi-slice T1 Mapping by using Slice Interleaved T1 (STONE) Sequence for the Detection of Diffuse Myocardial Fibrosis in Patients with Hypertrophic Cardiomyopathy

Shingo Kato 1 , Roujol Sbastien 1 , Jihye Jang 1 , Basha Tamer 1 , Berg Sophie 1 , Kissinger Kraig 1 , Goddu Beth 1 , Evan Appelbaum 1 , Martin Maron 2 , Warren J Manning 3 , and Nezafat Reza 3

1 Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States, 2 Division of Cardiology, Tufts Medical Center, Boston, Massachusetts, United States, 3 Department of Medicine and Radiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Myocardial T1 mapping in patients with hypertrophic cardiomyopathy (HCM) should be performed over the entire left ventricle due to regional variability of the location of the hypertrophic region. We have recently developed a free-breathing slice-interleaved T1 (STONE) mapping sequence which allows T1 mapping with complete coverage of LV during free-breathing in 1:30 min. Multi-slice T1 mapping by using STONE sequence could be advantageous to overcome limited cardiac coverage of conventional single-slice T1 mapping technique and to accurately detect the diffuse myocardial fibrosis in HCM patients.

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