Abstract #2679
R 1 - R 2 - R 2 * combined MR angiogram with dual contrast SPION
Hoesu Jung 1 , Sohyun Han 1 , Seokha Jin 1 , Dongkyu Lee 1 , and Hyungjoon Cho 1
1
Department of Biomedical Engineering, UNIST
(Ulsan National Institute of Science & Technology),
Ulsan, Gyeongsangnam-do, Korea
MR angiogram is used to investigate vascular malfunction
in brain. R1-weighted (T1-weighted) angiogram represents
accurate vessel information with positive enhancements,
but its sensitivity is low for smaller vasculature in
deep brain. Transverse relaxation based R2 and R2*
angiograms shows improved visibility in deep brain,
while vulnerable to susceptibility artifacts in the
vicinity of air-tissue interface and overestimation of
vessel size. In this study, we systematically compared
the strengths and weaknesses of R2, R2* and
R1-weighted angiograms. Conclusively, proposed R1- R2-
R2* combined angiogram presents the potential tool to
visualize a wide range of vasculature with minimized
susceptibility artifacts and enhanced sensitivity.
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