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Abstract #2679

R 1 - R 2 - R 2 * combined MR angiogram with dual contrast SPION

Hoesu Jung 1 , Sohyun Han 1 , Seokha Jin 1 , Dongkyu Lee 1 , and Hyungjoon Cho 1

1 Department of Biomedical Engineering, UNIST (Ulsan National Institute of Science & Technology), Ulsan, Gyeongsangnam-do, Korea

MR angiogram is used to investigate vascular malfunction in brain. R1-weighted (T1-weighted) angiogram represents accurate vessel information with positive enhancements, but its sensitivity is low for smaller vasculature in deep brain. Transverse relaxation based R2 and R2* angiograms shows improved visibility in deep brain, while vulnerable to susceptibility artifacts in the vicinity of air-tissue interface and overestimation of vessel size. In this study, we systematically compared the strengths and weaknesses of R2, R2* and R1-weighted angiograms. Conclusively, proposed R1- R2- R2* combined angiogram presents the potential tool to visualize a wide range of vasculature with minimized susceptibility artifacts and enhanced sensitivity.

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