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Abstract #2681

Intraindividual comparison of different contrast agent application schemes and their influence on concentration, signal and bolus geometry

Harald Kramer 1,2 , Gregor Jost 3 , Hubertus Pietsch 3 , and Maximilian F Reiser 1

1 Department of Clinical Radiology, University of Munich, Munich, Bavaria, Germany, 2 Department of Radiology, University of Wisconsin - Madison, Madison, Wisconsin, United States, 3 MR and CT Contrast Media Research, Bayer Healthcare, Berlin, Berlin, Germany

Although contrast enhanced (CE) techniques are well accepted as the standard of reference for most magnetic resonance angiography (MRA) applications, very little is known about the influence of contrast agent (CA) application schemes on CA bolus shape. Unlike iodinated CAs in computed tomography angiography (CTA) or conventional digital subtraction angiography (DSA), gadolinium (Gd) based CAs (GBCA) have a non-linear relationship between CA-concentration and MR signal. Published CA application approaches are highly variable between institutions and are based on anecdotal evidence only.

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