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Abstract #2715

Assessment of blood flow velocity and pulsatility in cerebral perforating arteries with 7T phase contrast MRI

Lennart J. Geurts 1 , Willem H. Bouvy 2 , Hugo J. Kuijf 3 , Peter R. Luijten 1 , L. Jaap Kappelle 2 , Geert Jan Biessels 2 , and Jaco J.M. Zwanenburg 1

1 Radiology, UMC Utrecht, Utrecht, Netherlands, 2 Neurology, UMC Utrecht, Utrecht, Netherlands, 3 Imaging Sciences Institute, UMC Utrecht, Utrecht, Netherlands

Reproducibility study at 7T for blood flow velocity measurements in cerebral perforating arteries.A single slice phase contrast sequence with 0.3x0.3x2.0mm voxels was used at three locations (medial cerebral artery:M1, basal ganglia:BG and semioval centre:CSO) in six healthy volunteers.Mean velocities (in cm/s) and their coefficients of repeatability (CoR) were 44(10) for M1, 4.6(1.9) for BG, 0.63(0.46) for CSO.The pulsatility index and its CoR was 0.56(0.24) for M1, 0.40(0.15) for BG and 0.28(0.14) for CSO.Blood flow velocity and pulsatility in cerebral perforating arteries may be an interesting new metric to study hemodynamic changes in ageing and cerebral small vessel disease.

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