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Abstract #2717

Contribution of early and late filling vortex rings to normal left ventricular flow: Quantitative 4D Flow MRI analysis using 3D vortex cores combined with particle tracing

Mohammed S.M. Elbaz 1 , Patrick J.H. de Koning 1 , Jos J.M. Westenberg 1 , Emmeline E. Calkoen 2 , Boudewijn P.F. Lelieveldt 1,3 , Arno A.W. Roest 2 , and Rob R.J. van der Geest 1

1 Division of Image Processing, Radiology, Leiden University Medical Center, Leiden, Netherlands, 2 Paediatric Cardiology, Leiden University Medical Center, Leiden, Netherlands, 3 Intelligent Systems, Delft University of Technology, Delft, Netherlands

Vortex formation in the left ventricle during diastolic filling has been confirmed by many in vivo and in vitro studies. Although many studies have postulated a potentially important role of vortex formation on the efficiency of cardiac pumping function, only limited knowledge is currently available on the actual contribution of the intrinsically three-dimensional vortex formation during diastole to the normal intra-cardiac blood flow in vivo. In this work, using 4D Flow MRI from ten healthy controls, we applied 3D vortex core analysis in combination with particle tracing to quantify the contribution of early and late filling 3D vortex rings to the normal LV flow over the cardiac cycle.

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